Synthroid Uses, Dosage & Side Effects

The recommended daily dosage of SYNTHROID in pregnant patients is described in Table 3. If so, advise them to stop biotin supplementation at least 2 days before assessing TSH and/or T4 levels see DOSAGE AND ADMINISTRATION and DRUG INTERACTIONS. Synthroid is also used in patients who need surgery and radioiodine therapy to manage a type of thyroid cancer called well-differentiated thyroid cancer. This list is not complete and many other drugs may interact with levothyroxine. This includes prescription and over-the-counter medicines, vitamins, and herbal products.

Pediatric Dosage

Biochemical assessment incorporated measurement of serum TSH, T3, and T4. TSH lower limit of quantification was 0.2 mIU/L and upper limit of normal was 5.6 mIU/L, as indicated by the shaded area. SYNTHROID is not indicated for treatment of hypothyroidism during the recovery phase of subacute thyroiditis. Note that cheap synthroid this list is not all-inclusive and includes only common medications that may interact with Synthroid. You should refer to the prescribing information for Synthroid for a complete list of interactions. SYNTHROID is contraindicated in patients with uncorrected adrenal insufficiency see WARNINGS AND PRECAUTIONS.

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of levothyroxine in children.

Important Considerations For Dosing

• And even the way you take Synthroid can affect how much medicine your body is getting.
• If your dose is different, do not change it unless your doctor tells you to do so.
• Atrial fibrillation is the most common of the arrhythmias observed with levothyroxine overtreatment in the elderly.
• Dr. Frieze suggests educating patients on the importance of consistent therapy & precise dosing with Synthroid.
• Cotton seed meal, dietary fiber, soybean flour (infant formula), or walnuts may decrease the absorption of this medicine from your body.
• Therefore, initiate SYNTHROID therapy immediately upon diagnosis.

All pregnancies have a background risk of birth defect, loss, or other adverse outcomes. In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2% to 4% and 15% to 20%, respectively. Concurrent use of tyrosine-kinase inhibitors such as imatinib may cause hypothyroidism.

Dosing And Administration

For adults, the usual suppressive dose of levothyroxine (T4) is 1.56 mcg/kg of body weight per day given for 7 to 10 days. These doses usually yield normal serum T4 and T3 levels and lack of response to TSH. For adult patients with primary hypothyroidism, titrate until the patient is clinically euthyroid and the serum TSH returns to normal see Dosage and Administration (2.3). For adult patients with primary hypothyroidism, titrate until the patient is clinically euthyroid and the serum TSH returns to normal see Recommended Dosage And Titration. Biotin supplementation may interfere with immunoassays for TSH, T4, and T3, resulting in erroneous thyroid hormone test results. Inquire whether patients are taking biotin or biotin-containing supplements.

• This is important because the amount of medicine you need is very precise.
• Approximately 80% of the daily dose of T4 is deiodinated to yield equal amounts of T3 and reverse T3 (rT3).
• Levothyroxine injection is used in adults to treat myxedema coma.

More about levothyroxine

If so, advise them to stop biotin supplementation at least 2 days before assessing TSH and/or T4 levels (see PRECAUTIONS). Addition of levothyroxine therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. Carefully monitor glycemic control after starting, changing, or discontinuing SYNTHROID see Drug Interactions (7.2). Initiate SYNTHROID therapy in this population at lower doses than those recommended in younger individuals or in patients without cardiac disease see Dosage and Administration (2.3) and Use in Specific Populations (8.5). For adult patients with primary hypothyroidism, titrate until the patient is clinically euthyroid and the serum TSH returns to normal. Levothyroxine is used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone.

When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of levothyroxine in the elderly.

Take levothyroxine tablets and capsules on an empty stomach, at least 30 to 60 minutes before breakfast with a full glass of water. Levothyroxine belongs to a class of medications called hormones. It works by replacing thyroid hormone that is normally produced by the body.

Nephrosis, severe hypoproteinemia, severe liver disease, acromegaly, androgens, and corticosteroids decrease TBG concentration. Familial hyper- or hypo-thyroxine binding globulinemias have been described, with the incidence of TBG deficiency approximating 1 in 9000. Consumption of certain foods may affect SYNTHROID absorption thereby necessitating adjustments in dosing see DOSAGE AND ADMINISTRATION. Synthroid should not be used to treat obesity or weight problems. Dangerous side effects or death can occur from the misuse of levothyroxine, especially if you are taking any other weight-loss medications or appetite suppressants. Synthroid is a thyroid medicine that replaces a hormone normally produced by your thyroid gland to regulate the body’s energy and metabolism.

Generally, thyroid replacement treatment is to be taken for life. SYNTHROID should not be used to treat noncancerous growths or enlargement of the thyroid in patients with normal iodine levels, or in cases of temporary hypothyroidism caused by inflammation of the thyroid gland (thyroiditis). Myxedema coma is usually precipitated in the hypothyroid patient of long-standing by intercurrent illness or drugs such as sedatives and anesthetics and should be considered a medical emergency. Therapy should be directed at the correction of electrolyte disturbances and possible infection besides the administration of thyroid hormones. Levothyroxine (T4) and liothyronine (T3) may be administered via a nasogastric tube but the preferred route of administration of both hormones is intravenous. Levothyroxine sodium (T4) is given at a starting dose of 400 mcg (100 mcg/mL) given rapidly, and is usually well tolerated, even in the elderly.